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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDM16 All Species: 4.24
Human Site: S859 Identified Species: 8.48
UniProt: Q9HAZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAZ2 NP_071397.2 1276 140251 S859 P L H Y A K P S P F F M D P I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093583 1230 138131 R834 P I Y R V E K R K L T D P L E
Dog Lupus familis XP_536720 1330 145448 P932 P S L H Y A K P S P F F M D P
Cat Felis silvestris
Mouse Mus musculus A2A935 1275 140840 P859 P S L H Y A K P S P F F M D P
Rat Rattus norvegicus XP_002726668 1257 138805 S860 S L H Y A K P S P F F M D P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508323 979 106177 F598 D A S D G S D F E D V N T T T
Chicken Gallus gallus XP_417551 908 100815 Q527 G P G F M G M Q E K K M G S L
Frog Xenopus laevis B7ZRU9 1055 118966 P674 F L F H P Q F P M P D Q R T W
Zebra Danio Brachydanio rerio XP_001922927 1153 129171 F772 L R P T P L L F H P Q V S A M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8I7Z8 990 109209 K609 Q Q A E D D R K S I D I M S T
Honey Bee Apis mellifera XP_001121599 1541 171480 K1073 P E R R A G A K P R V I E A G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798234 1723 193143 L1338 A F S Y P G G L P I T M D P M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 53.9 83.4 N.A. 88.2 86.2 N.A. 57.1 59.9 45.4 61.2 N.A. 27.5 21.8 N.A. 20.8
Protein Similarity: 100 N.A. 68 87.8 N.A. 91.8 90.1 N.A. 62.1 64.5 57.2 71.9 N.A. 39.9 35.3 N.A. 35.8
P-Site Identity: 100 N.A. 6.6 13.3 N.A. 13.3 93.3 N.A. 0 6.6 6.6 0 N.A. 0 20 N.A. 33.3
P-Site Similarity: 100 N.A. 26.6 20 N.A. 20 93.3 N.A. 0 20 20 13.3 N.A. 6.6 33.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 0 25 17 9 0 0 0 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 9 9 9 0 0 9 17 9 25 17 0 % D
% Glu: 0 9 0 9 0 9 0 0 17 0 0 0 9 0 9 % E
% Phe: 9 9 9 9 0 0 9 17 0 17 34 17 0 0 0 % F
% Gly: 9 0 9 0 9 25 9 0 0 0 0 0 9 0 9 % G
% His: 0 0 17 25 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 17 0 17 0 0 17 % I
% Lys: 0 0 0 0 0 17 25 17 9 9 9 0 0 0 0 % K
% Leu: 9 25 17 0 0 9 9 9 0 9 0 0 0 9 9 % L
% Met: 0 0 0 0 9 0 9 0 9 0 0 34 25 0 17 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 42 9 9 0 25 0 17 25 34 34 0 0 9 25 17 % P
% Gln: 9 9 0 0 0 9 0 9 0 0 9 9 0 0 0 % Q
% Arg: 0 9 9 17 0 0 9 9 0 9 0 0 9 0 0 % R
% Ser: 9 17 17 0 0 9 0 17 25 0 0 0 9 17 0 % S
% Thr: 0 0 0 9 0 0 0 0 0 0 17 0 9 17 17 % T
% Val: 0 0 0 0 9 0 0 0 0 0 17 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 9 25 17 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _